The sodium-potassium pump actively maintains cellular resting potential using ATP
Is it true that the sodium-potassium pump actively maintains cellular resting potential using ATP?
Yes. Multiple scientific reviews confirm that the sodium-potassium pump actively utilizes energy derived from ATP hydrolysis to transport ions and maintain cellular electrochemical and resting potentials.
Verdict: SUPPORTED · 3 sources for, 0 against · Last checked
The claim states that the sodium-potassium pump actively maintains cellular resting potential using ATP. Retrieved papers such as [2], [5], and [10] explicitly discuss the Na+/K+-ATPase pump utilizing ATP hydrolysis to transport sodium and potassium ions and maintain ionic gradients/homeostasis. No papers refute this fundamental physiological fact.
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Contreras, R. G., Torres-Carrillo, A., Flores-Maldonado, C., Shoshani, L., & Ponce, A. (2024). Na+/K+-ATPase: More than an Electrogenic Pump. doi.org. https://doi.org/10.3390/ijms25116122
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McKenna, M. J., Renaud, J., Ørtenblad, N., & Overgaard, K. (2024). A century of exercise physiology: effects of muscle contraction and exercise on skeletal muscle Na+,K+-ATPase, Na+ and K+ ions, and on plasma K+ concentration—historical developments. doi.org. https://doi.org/10.1007/s00421-023-05335-9
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Gao, Y., Xu, Y., Bai, F., Puri, R., Tian, J., & Liu, J. (2025). Factors that influence the Na/K-ATPase signaling and function. doi.org. https://doi.org/10.3389/fphar.2025.1639859
What does the evidence say?
The claim states that the sodium-potassium pump actively maintains cellular resting potential using ATP. Retrieved papers such as [2], [5], and [10] explicitly discuss the Na+/K+-ATPase pump utilizing ATP hydrolysis to transport sodium and potassium ions and maintain ionic gradients/homeostasis. No papers refute this fundamental physiological fact.
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