The claim that the human brain cannot feel pain is refuted by medical evidence showing that intracranial structures, such as blood vessels and meninges, contain nociceptors and that the central nervous system processes pain signals.
The claim is a common physiological misconception. While the brain parenchyma itself lacks traditional nociceptors (which is why awake brain surgery can be performed without general anesthesia once the scalp is numbed), intracranial structures like the dura mater and cerebral blood vessels are heavily innervated by pain-sensing fibers and can distinctly perceive pain, as demonstrated in neurosurgical and migraine research.