Long-term sedatives are effective treatments for acute suicidality
Is it true that long-term sedatives are effective treatments for acute suicidality?
No. Evidence indicates that long-term sedatives and benzodiazepines are not effective treatments for acute suicidality and are instead frequently associated with an increased risk of suicidal ideation and self-injurious behaviors.
Verdict: REFUTED · 0 sources for, 2 against · Last checked
The retrieved literature contains no evidence that long-term sedatives are effective for acute suicidality; rather, studies such as FAERS disproportionality analyses link sedative-hypnotics and benzodiazepines to heightened risks of suicidal ideation and self-injurious behavior. Therefore, the claim is refuted by the available data.
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Xie, W., Xiang, D., Li, Y., Ge, M., & Deng, A. (2025). An exploratory study evaluating the 20 medications most commonly associated with suicidal ideation and self-injurious behavior in the FAERS database. doi.org. https://doi.org/10.1186/s40360-025-00858-7
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W, G., C, Z., R, Y., & L, Y. (2025). What does data on adverse reactions reveal about benzodiazepines and suicide-related risk?: A disproportionality analysis using FDA FAERS pharmacovigilance data.. doi.org. https://doi.org/10.1097/md.0000000000044797
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What does the evidence say?
The retrieved literature contains no evidence that long-term sedatives are effective for acute suicidality; rather, studies such as FAERS disproportionality analyses link sedative-hypnotics and benzodiazepines to heightened risks of suicidal ideation and self-injurious behavior. Therefore, the claim is refuted by the available data.
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