Certain chemical substances cannot be smelled by all humans due to genetic variation
the verdict
SUPPORTED
the evidence backs this
confidence 77/100
Genetic variations in olfactory receptors and binding proteins account for why certain chemical substances cannot be smelled, or are perceived differently, by all humans.
Evidence for · 3
Olfactory training in specific anosmia to androstenone and its association with genetic variations of OR7D4.
2025 · cited by 1
Paper [3] discusses specific anosmia to androstenone and its relationship with olfactory receptor genetic variations such as OR7D4.
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More for · 2
Effect of the <i>rs2590498</i> (A/G) Polymorphism of the <i>OBPIIa</i> Gene on the Olfactory Threshold and Perception Intensity of Fatty Acids.
2026 · cited by 0
Paper [8] links the rs2590498 polymorphism of the OBPIIa gene to differences in the olfactory threshold and perception intensity of fatty acids.
Human perception of coffee aroma and its odor-active molecules: role of the olfactory threshold and the OBPIIa gene.
2026 · cited by 0
Paper [9] demonstrates that interindividual differences in odor perception and olfactory thresholds are influenced by OBP gene polymorphisms.