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Genetic variation influences basal metabolic rate in humans.

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INSUFFICIENT LEANING
Recorded sources
6 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that genetic variation influences basal metabolic rate in humans?

Unclear. Several peer-reviewed sources indicate a genetic component to basal metabolic rate variation, including a review concluding within-species BMR variation has a clear genetic signature and a study linking a specific regulatory variant to BMR in humans. However, the human-specific evidence is limited to particular populations or single variants, and much of the support comes from mouse or cross-species work.

Verdict: PARTIAL LEAN · 6 sources for, 0 against · Last checked

The private library was unavailable for some searches in this check. Missing library results are not evidence against the claim.

Evidence for · 6
Determinants of intra-specific variation in basal metabolic rate
2012
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Konarzewski, M. & Książek, A. (2012). Determinants of intra-specific variation in basal metabolic rate. doi.org. https://doi.org/10.1007/s00360-012-0698-z

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More for · 5
Basal metabolic rate shapes the development and progression of hepatocellular carcinoma
2025
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Maciak, S., Sawicka, D., Kasacka, I., Chyczewski, L., Car, H., & Konarzewski, M. (2025). Basal metabolic rate shapes the development and progression of hepatocellular carcinoma. doi.org. https://doi.org/10.1186/s12885-025-14491-4

Climatic influences on basal metabolic rates among circumpolar populations
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Climatic influences on basal metabolic rates among circumpolar populations. (n.d.). cir.nii.ac.jp. https://doi.org/10.1002/ajhb.10072

An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis
2025
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Zhang, Y., Wang, J., Yi, C., Su, Y., Yin, Z., Zhang, S., Jin, L., Stoneking, M., Yang, J., Wang, K., Huang, H., Li, J., & Fan, S. (2025). An ancient regulatory variant of ACSF3 influences the coevolution of increased human height and basal metabolic rate via metabolic homeostasis. doi.org. https://doi.org/10.1016/j.xgen.2025.100855

A novel polymorphism in the fatty acid desaturase 2 gene ( Fads2 ): A possible role in the basal metabolic rate
2019
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Czajkowska, M., Brzęk, P., & Dobrzyń, P. (2019). A novel polymorphism in the fatty acid desaturase 2 gene ( Fads2 ): A possible role in the basal metabolic rate. doi.org. https://doi.org/10.1371/journal.pone.0213138

Meta-analysis of the heritability of human traits based on fifty years of twin studies.
2015
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Polderman, T. J. C., Benyamin, B., Leeuw, C. A. d., Sullivan, P. F., Bochoven, A. v., Visscher, P. M., & Posthuma, D. (2015). Meta-analysis of the heritability of human traits based on fifty years of twin studies.. doi.org. https://doi.org/10.1038/ng.3285

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