Psoriasis systematically alters the inflammatory biochemistry of the blood
Clinical studies consistently show that psoriasis is associated with systemic changes in blood inflammatory biochemistry, including elevated C-reactive protein, white blood counts, and specific biomarkers like FABP5.
The claim posits that psoriasis systematically alters the inflammatory biochemistry of the blood. All three retrieved papers support this by reporting elevated inflammatory markers and metabolic proteins in the serum of psoriasis patients compared to healthy controls. There are no refuting papers.
Berna Solak, Bahar Sevimli Dikicier, Teoman Erdem. Impact of Elevated Serum Uric Acid Levels on Systemic Inflammation in Patients With Psoriasis. 2016. https://doi.org/10.1177/0003319716657980
This study found that patients with psoriasis exhibit elevated systemic inflammation markers, such as CRP, white blood cell count, and neutrophil to lymphocyte ratio, compared to healthy controls.
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Dorota Kozłowska, Hanna Myśliwiec, Ewa Harasim-Symbor, Anna Milewska, Adrian Chabowski, Iwona Flisiak. Serum Fatty Acid Binding Protein 5 (FABP5) as a Potential Biomarker of Inflammation in Psoriasis.. 2020. https://doi.org/10.21203/rs.3.rs-41783/v1
This study demonstrated that serum FABP5 levels are significantly higher in psoriatic patients and correlate with basic inflammation indices like CRP, supporting systemic biochemical alterations.
Dorota Kozłowska, Hanna Myśliwiec, Ewa Harasim-Symbor, Anna Justyna Milewska, Adrian Chabowski, Iwona Flisiak. Serum Fatty Acid Binding protein 5 (FABP5) as a Potential Biomarker of Inflammation in Psoriasis.. 2020. https://doi.org/10.21203/rs.3.rs-101777/v1
This duplicate study similarly reported elevated serum FABP5 and its positive correlation with inflammatory markers in patients with psoriasis.
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