Biological amino acids are exclusively homochiral due to prebiotic chemical selection
Current prebiotic chemistry models and experiments demonstrate that small initial enantiomeric imbalances in amino acids can be amplified through processes like sublimation, autocatalysis, and kinetic resolution to achieve biological homochirality.
The retrieved papers provide robust evidence supporting the claim that biological homochirality arose from prebiotic chemical selection and amplification mechanisms. Papers 0, 1, and 3 all detail specific prebiotic or chemical processes (sublimation, autocatalytic models, and reaction-based amplification) that explain how a racemic mixture can evolve toward homochirality. No papers refute this claim.
Arkadii V. Tarasevych, Alexander E. Sorochinsky, Valery P. Kukhar, Jean-Claude Guillemin. High temperature sublimation of α-amino acids: a realistic prebiotic process leading to large enantiomeric excess. 2015. https://doi.org/10.1039/c5cc00254k
Demonstrates that high temperature sublimation of racemic amino acids with enantioenriched derivatives leads to large enantiomeric excesses.
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Donna Blackmond. Autocatalytic Models for the Origin of Biological Homochirality. 2019. https://doi.org/10.26434/chemrxiv.9916235.v1
Discusses mechanistic models of autocatalysis, such as the Soai reaction, relevant to the origin of biological homochirality.
Huajie Zhu, Yunjin Jia, Zhiwei Li, Yujun Zhu, Charles Pittman, Jr. Amplification of Enantiomeric Excess without Any Chiral Source in Prebiotic Case. 2023. https://doi.org/10.20944/preprints202307.0287.v1
Shows that small initial enantiomeric excesses in prebiotic molecules can be amplified to high levels through chemical processes without an initial chiral source.
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