A healthy adult should take a daily multi-vitamin
Large-scale systematic reviews and randomized clinical trials indicate that daily multivitamin supplementation does not provide significant health benefits, such as reducing cardiovascular disease or fracture risk, for healthy adults.
The claim asserts that healthy adults should take a daily multivitamin. The provided literature includes a large systematic review and meta-analysis showing no cardiovascular benefits from multivitamins (Paper 0), as well as a recent large-scale randomized clinical trial finding no reduction in fracture risk from multivitamin use (Paper 1). Papers 2, 3, and 4 are completely unrelated. Because rigorous empirical evidence shows no significant health benefits for general multivitamin use, the claim is refuted.
Joonseok Kim, Jaehyoung Choi, Soo Young Kwon, John W. McEvoy, Michael J. Blaha, Roger S. Blumenthal, Eliseo Guallar, Di Zhao, Erin D. Michos. Association of Multivitamin and Mineral Supplementation and Risk of Cardiovascular Disease. 2018. https://doi.org/10.1161/circoutcomes.117.004224
This meta-analysis demonstrates that multivitamin and mineral supplementation does not improve cardiovascular outcomes or reduce mortality in the general population.
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Carolyn J Crandall, Sharon Chou, Eunjung Kim, Dana Ratnarajah, Nancy R Cook, Allison Clar, Howard D Sesso, JoAnn E Manson, Meryl S LeBoff. Effects of cocoa extract supplementation and multivitamin/multimineral supplements on self-reported fractures in the Cocoa Supplement and Multivitamins Outcomes Study randomized clinical trial. 2025. https://doi.org/10.1093/jbmr/zjaf030
This randomized clinical trial found that multivitamin/multimineral supplementation does not reduce the risk of clinical fractures or nonvertebral fractures in older adults.
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