Mitochondria can develop mutations associated with cancerous transformation.

the verdict

SUPPORTED

the evidence backs this

Recorded sources

2 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Multiple studies and reviews document the presence and detection of mitochondrial DNA mutations in human cancers.

The analysis

The claim asserts that mitochondria can develop mutations associated with cancerous transformation. Papers [8] and [11] explicitly mention that mutations of the mitochondrial genome have been detected in human cancers, supporting the claim. The remaining papers discuss mitochondrial dysfunction in cancer but do not explicitly focus on mitochondrial mutations leading to transformation, meaning they are tangential.

Evidence for · 2

Mitochondrial DNA mutations in ageing and cancer.

Recorded source metadata

Anna L M Smith, Julia C Whitehall, Laura C Greaves. Mitochondrial DNA mutations in ageing and cancer.. 2022. https://doi.org/10.1002/1878-0261.13291

States that mutations of the mitochondrial genome (mtDNA) have been reported in human cancers for decades and discusses how mitochondrial alterations relate to age-related cancer development.

Source citation format

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More for · 1

Comprehensive review on lactate metabolism in human health.

Recorded source metadata

M Adeva-Andany, M López-Ojén, R Funcasta-Calderón, E Ameneiros-Rodríguez, C Donapetry-García, M Vila-Altesor, J Rodríguez-Seijas. Comprehensive review on lactate metabolism in human health.. 2014. https://doi.org/10.1016/j.mito.2014.05.007

Notes that mitochondrial DNA mutations have been detected in a number of human cancers.

Source citation format

The paper trail · every fact has a biography

first checked01 Aug 2026

judged → SUPPORTED · 7501 Aug 2026

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