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the claim

Certain organisms incorporate metal ions like iron and copper into their biological structures

the verdict
SUPPORTED
the evidence backs this
Recorded sources
7 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Numerous biological studies and reviews confirm that living organisms incorporate essential metal ions such as iron and copper into their structures, enzymes, and proteins.

The analysis

The claim is specific, empirical, and well-supported by multiple peer-reviewed papers demonstrating that organisms incorporate metal ions like iron and copper into biological structures (e.g., metalloproteins, cuproenzymes, and metal-sulfide centers). Therefore, the balance verdict is SUPPORTED.

Evidence for · 7
Recorded source metadata

Leilei Chen, Qing-qing Shen, Yingjuan Liu, Yunqi Zhang, Liping Sun, Xizhen Ma, Ning Song, Junxia Xie. Homeostasis and metabolism of iron and other metal ions in neurodegenerative diseases. 2025. https://doi.org/10.1038/s41392-024-02071-0

Paper 0 details how essential metal ions like iron and copper are integrated into physiological processes within biological structures.

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More for · 6
Recorded source metadata

K. Jomová, Suliman Y. Alomar, Richard Valko, E. Nepovimova, Kamil Kuča, Marian Valko. The role of redox-active iron, copper, manganese, and redox-inactive zinc in toxicity, oxidative stress, and human diseases. 2025. https://doi.org/10.17179/excli2025-8449

Paper 1 discusses the key roles of redox-active metals such as iron and copper in vital cellular structures and functions.

Recorded source metadata

Klaudia Jomova, Marianna Makova, Suliman Y Alomar, Saleh H Alwasel, Eugenie Nepovimova, Kamil Kuca, Christopher J Rhodes, Marian Valko. Essential metals in health and disease.. 2022. https://doi.org/10.1016/j.cbi.2022.110173

Paper 7 identifies d-block transition metal elements like iron and copper as essential components for the correct functioning of biological organisms.

Recorded source metadata

Jenifer Calvo, Hunmin Jung, Gabriele Meloni. Copper metallothioneins.. 2017. https://doi.org/10.1002/iub.1618

Paper 8 describes copper metallothioneins, which bind transition metals into specific structures to control homeostasis.

Recorded source metadata

Martha E Sosa Torres, Peter M H Kroneck. Introduction: Transition Metals and Sulfur.. 2020. https://doi.org/10.1515/9783110589757-007

Paper 9 explains how transition metal ions are incorporated into active sites and sulfur-containing biological structures.

Recorded source metadata

Biplab K Maiti, Luisa B Maia, José J G Moura. Sulfide and transition metals - A partnership for life.. 2022. https://doi.org/10.1016/j.jinorgbio.2021.111687

Paper 10 discusses how transition metals form structural metal-sulfide centers to fulfill physiological roles in living organisms.

Recorded source metadata

B L O'Dell. Biochemistry of copper.. 1976. https://doi.org/10.1016/s0025-7125(16)31853-3

Paper 11 notes that copper acts as a structural component of numerous cuproenzymes crucial for physiological functions in humans and animals.

The paper trail · every fact has a biography
first checked01 Aug 2026
judged → SUPPORTED · 8901 Aug 2026
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