Autism spectrum disorders are exclusively inherited genetic traits
Autism spectrum disorder is not exclusively an inherited genetic trait; current research demonstrates that it involves complex genetic heterogeneity alongside important epigenetic and environmental contributions. (e.g., [0], [1]).
The claim states that autism spectrum disorders are exclusively inherited genetic traits. Both retrieved papers discuss complex genetic architectures, heterogeneity, and additional epigenetic factors like DNA methylation, directly refuting the idea that they are exclusively inherited genetic traits. Therefore, the verdict is REFUTED.
Arjun Krishnan, Ran Zhang, Victoria Yao, Chandra L. Theesfeld, Aaron K. Wong, Alicja Tadych, Natalia Volfovsky, Alan Packer, Alex Lash, Olga G. Troyanskaya. Genome-wide characterization of genetic and functional dysregulation in autism spectrum disorder. 2016. https://doi.org/10.1101/057828
Paper 0 establishes that while autism spectrum disorder has a strong genetic basis, it exhibits extensive genetic heterogeneity and complex modes of inheritance rather than being exclusively inherited.
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Sofia Stathopoulos, Renaud Gaujoux, Colleen O’Ryan. Genome-wide DNA methylation patterns in Autism Spectrum Disorder and mitochondrial function. 2018. https://doi.org/10.1101/310748
Paper 1 highlights that epigenetic mechanisms, particularly DNA methylation and mitochondrial function, also play crucial roles in the etiology of autism spectrum disorder, contradicting the claim that it is exclusively genetic.
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