CO2 laser treatment is effective for treating acne scars

G. Faghihi, Shima Keyvan, A. Asilian, Saeid Nouraei, S. Behfar, M. Nilforoushzadeh. Efficacy of autologous platelet-rich plasma combined with fractional ablative carbon dioxide resurfacing laser in treatment of facial atrophic acne scars: A split-face randomized clinical trial. 2016. https://doi.org/10.4103/0378-6323.174378

A randomized clinical trial demonstrates significant clinical improvement of atrophic acne scars using fractional carbon dioxide laser therapy.

Y. Mu, Lu Jiang, Hao Yang. The efficacy of fractional ablative carbon dioxide laser combined with other therapies in acne scars. 2019. https://doi.org/10.1111/dth.13084

A review highlights that fractional carbon dioxide laser resurfacing effectively improves skin regeneration and serves as a frontline treatment for acne scars.

E. M. Abdel-Maguid, S. Awad, Youssef Hassan, M. El-Mokhtar, Heba E M El-Deek, M. M. Mekkawy. Efficacy of stem cell-conditioned medium vs. platelet-rich plasma as an adjuvant to ablative fractional CO2 laser resurfacing for atrophic post-acne scars: a split-face clinical trial. 2019. https://doi.org/10.1080/09546634.2019.1630701

A clinical trial shows that ablative fractional CO2 laser resurfacing effectively increases dermal collagen and improves atrophic post-acne scars.

M. Nilforoushzadeh, G. Faghihi, F. Jaffary, Elaheh Haftbaradaran, S. Hoseini, N. Mazaheri. Fractional Carbon Dioxide Laser and its Combination with Subcision in Improving Atrophic Acne Scars. 2017. https://doi.org/10.4103/2277-9175.201332

A clinical trial indicates that fractional carbon dioxide laser effectively improves atrophic acne scars, particularly with high patient satisfaction.

H. Gawdat, Yasmin Ahmed El-Hadidy, R. Allam, H. Abdelkader. Autologous platelet-rich plasma ‘fluid’ versus ‘gel’ form in combination with fractional CO2 laser in the treatment of atrophic acne scars: a split-face randomized clinical trial. 2022. https://doi.org/10.1080/09546634.2022.2067816

A randomized clinical trial shows that fractional CO2 laser combined with plasma therapies produces significant results in treating atrophic acne scars.

Chinathip Theerawattanawit, T. Promvaranon, P. Rerknimitr, P. Asawanonda, N. Noppakun, C. Kumtornrut. Snail Soothing and Repairing Cream Improves Skin Hydration after Ablative Fractional CO2 Laser: A Split-Face Randomized Double-Blinded Placebo-Controlled Trial. 2021. https://doi.org/10.1159/000515965

A study evaluates the use of skincare adjuncts following ablative fractional CO2 laser resurfacing for atrophic acne scars.

F. Abel, Kallappa C. Herakal, Nikhita Shetty. A comparative study of efficacy of resurfacing with fractional carbon dioxide laser versus derma roller in the treatment of post acne scars. 2020. https://doi.org/10.18203/issn.2455-4529.intjresdermatol20203074

A comparative study demonstrates that fractional carbon dioxide laser is highly effective in reducing post-acne scar scores.

Hang X, Lim DS. A Novel Peel to Prevent Post-Inflammatory Hyperpigmentation After CO<sub>2</sub> Resurfacing for Acne Scars.. 2025. https://doi.org/10.1111/jocd.70366

A study confirms that fractional carbon dioxide laser resurfacing is an effective treatment for atrophic acne scars while evaluating methods to mitigate post-inflammatory hyperpigmentation.