Human physiological limits define precise maximum and minimum core body temperatures for survival

the verdict

SUPPORTED

the evidence backs this

Recorded sources

3 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Human survival is bounded by distinct physiological and environmental temperature limits, outside of which thermoregulation fails and core body temperatures become unsustainable.

The analysis

The retrieved literature consistently supports the concept that human thermoregulation operates within bounded physiological limits, beyond which core temperatures lead to severe morbidity or mortality. Studies specifically establish empirical limits and core temperature thresholds for both hypothermia and hyperthermia.

Evidence for · 3

Physiological Impact of Hypothermia: The Good, the Bad, and the Ugly.

Recorded source metadata

Torkjel Tveita, Gary C Sieck. Physiological Impact of Hypothermia: The Good, the Bad, and the Ugly.. 2022. https://doi.org/10.1152/physiol.00025.2021

Paper 1 discusses how hypothermia is defined below specific core temperature thresholds (such as <35°C), beyond which physiological systems fail and circulatory collapse can occur.

Source citation format

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More for · 2

Critical environmental core temperature limits and heart rate thresholds across the adult age span (PSU HEAT Project).

Recorded source metadata

Rachel M Cottle, Kat G Fisher, Olivia K Leach, S Tony Wolf, W Larry Kenney. Critical environmental core temperature limits and heart rate thresholds across the adult age span (PSU HEAT Project).. 2024. https://doi.org/10.1152/japplphysiol.00117.2024

Paper 7 establishes critical environmental core temperature and heart rate limits across adult ages, highlighting precise thresholds beyond which thermoregulation is compromised.

Source citation format

Validating new limits for human thermoregulation.

Recorded source metadata

Robert D Meade, Fergus K O'Connor, Brodie J Richards, Emily J Tetzlaff, Katie E Wagar, Roberto C Harris-Mostert, Theodore Egube, James J McCormick, Glen P Kenny. Validating new limits for human thermoregulation.. 2025. https://doi.org/10.1073/pnas.2421281122

Paper 8 validates empirical limits for human thermoregulation, demonstrating specific wet-bulb temperature inflection points where core body temperature rises uncontrollably toward dangerous levels.

Source citation format

The paper trail · every fact has a biography

first checked01 Aug 2026

judged → SUPPORTED · 7501 Aug 2026

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