Ingesting nicotine from cigarettes can lead to fatal overdoses
Clinical and historical evidence indicates that ingesting high doses of nicotine from tobacco products or alternatives can cause acute poisoning, severe respiratory failure, and potentially fatal overdoses.
The retrieved literature contains specific case documentation demonstrating that acute nicotine poisoning from ingestion can lead to severe toxic reactions and respiratory failure, aligning with the claim that nicotine ingestion can cause fatal overdoses. Papers [2] and [6] directly discuss acute nicotine toxicity via ingestion routes.
BYRON B. OBERST, ROSS A. MCINTYRE. ACUTE NICOTINE POISONING. 1953. https://doi.org/10.1542/peds.11.4.338
This historical case study documents acute nicotine poisoning resulting from the administration of a tobacco infusion, highlighting the severe systemic toxicity of ingested nicotine.
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Jung Eun Lee, Tae Chang Jang, Young Woo Seo. Unintentional fatal toxicity due to nicotine chewing gum: A case report. 2022. https://doi.org/10.1097/md.0000000000031225
This clinical report describes acute respiratory failure and severe poisoning resulting from the excessive oral ingestion of nicotine replacement products, demonstrating the potential for fatal-level toxicity.
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