Maintaining a circadian rhythm is essential for optimal physiological function

Tanasescu MD, Rosu AM, Minca A, Grigorie MM, Timofte D, Ionescu D. Adipose Tissue Circadian Dysregulation Beyond BMI: Implications for Cardiometabolic Risk and Cardiovascular Disease.. 2026. https://doi.org/10.3390/life16020305

The paper demonstrates that circadian misalignment in adipose tissue impairs metabolic coordination and exacerbates cardiometabolic risk.

Jun-Yan Liu. Physiological and Pathological Insights into the Circadian Rhythm of Polyunsaturated Fatty Acids Metabolism. 2025. https://doi.org/10.53941/hm.2025.100017

The study outlines how circadian clocks regulate polyunsaturated fatty acid metabolism, influencing cardiovascular and metabolic health.

Michael Jackson Oliveira de Andrade. Circadian Sensation and Visual Perception. 2022. https://doi.org/10.5772/intechopen.100591

This review details how biological rhythms govern fundamental physiological functions, neural activity, and sensory perception.

Shannon M. Bailey. Timing matters: circadian rhythm disruption in alcohol-associated peripheral organ pathophysiology. 2026. https://doi.org/10.1152/function.099.2025

The research shows how circadian disruption exacerbates alcohol-induced organ injury, inflammation, and metabolic dysfunction.

Alina Crenguța Nicolae, Ion-Bogdan Dumitrescu, Camelia Cristina Diaconu, Mirela Elena Ritivoiu, Carmen Adella Sirbu, Cristina Manuela Drăgoi. Chronotherapy Advances in the Management of Chronic Neurological and Cardiovascular Diseases: Complex Interactions of Circadian Rhythm Environmental Inputs, Nutrition and Drug Administration and Their Impact on Human Health. 2022. https://doi.org/10.5772/intechopen.106950

This review emphasizes that biological rhythms modulate drug pharmacokinetics and overall physiological homeostasis across various health conditions.

Melone MA, Gehlbach BK. Sleep, circadian rhythms and outcomes in intensive care unit.. 2026. https://doi.org/10.3389/fneur.2026.1790266

The study notes that sleep and circadian dysrhythmias in critical care are closely tied to inflammation, organ dysfunction, and clinical outcomes.

Liu K, Lv X, Wen W. Clocking immunity: circadian modulation of NK cells and emerging timing perspectives.. 2026. https://doi.org/10.3389/fimmu.2026.1739723

The article demonstrates that circadian timing modulates immune cell function, whereas disruption impairs immune defense and increases vulnerability.

Liu BT, Chen Y, Zhu YL, Ren SC, Wang JF. Circadian Rhythms in Acute Respiratory Distress Syndrome: Molecular Mechanisms and Therapeutic Implications.. 2026. https://doi.org/10.3390/ijms27104206

The review establishes that core clock disruption contributes to alveolar-capillary barrier dysfunction and severe inflammation in acute respiratory distress syndrome.

Saeed S, Sang R, Zhixin L, Wang H, Xu L, Zhang X, Hu S. Circadian rhythms in major depressive disorder: mechanistic insights and therapeutic frontiers.. 2026. https://doi.org/10.1080/07853890.2026.2671594

The study reveals that circadian system disruption is fundamental to the pathophysiology of major depressive disorder.

Biliński K, Wiśniewski K, Rafner L, Witko P, Gaweł-Dąbrowska D. Travel-Induced Circadian and Microbiota Disturbances: Implications for Athlete Health and Performance: A Narrative Review.. 2026. https://doi.org/10.3390/nu18101523

This review illustrates that circadian desynchronization from travel impairs metabolic regulation, gut integrity, and overall physiological resilience.