Medical laboratories determine accuracies for their blood tests
Medical laboratories routinely perform validation, precision, and performance evaluations to determine the accuracy of their diagnostic blood and fluid tests.
The retrieved papers consistently demonstrate that medical and clinical laboratories conduct analytical validations, performance evaluations, and method comparisons to determine the accuracy and reliability of various blood tests and diagnostic assays.
David H Wilson, D. Chan, Lei Chang, Robert Mathis, I. Verberk, X. Montalban, M. Comabella, N. Fissolo, B. Bielekova, R. Masvekar, Tanuja Chitnis, Tjalf Ziemssen, Katja Akgün, K. Blennow, H. Zetterberg, Wolfgang Brück, G. Giovannoni, S. Gnanapavan, S. Bittner, F. Zipp, G. Comi, Roberto Furlan, Sylvain Lehmann, S. Thebault, M. Freedman, A. Bar-Or, M. Kramer, Markus Otto, S. Halbgebauer, K. Hrusovsky, T. Plavina, M. Khalil, F. Piehl, H. Wiendl, L. Kappos, A. Maceski, Eline Willemse, D. Leppert, C. Teunissen, J. Kuhle. Development and multi-center validation of a fully automated digital immunoassay for neurofilament light chain: toward a clinical blood test for neuronal injury. 2023. https://doi.org/10.1515/cclm-2023-0518
This study evaluates the analytical performance and multi-center validation of a clinical blood test.
See more details
Moritz Waldecker, Schessler Katherina, Bömicke Wolfgang, Rammelsberg Peter, Rues Stefan. In-vitro validation of a new method to assess the clinical accuracy of complete arch impressions. 2025. https://doi.org/10.1007/s00784-025-06236-1
This paper evaluates an in vitro method to assess the clinical accuracy of diagnostic dental impressions.
S. Moon, H. Choi, Serim Kim, Kyunghoon Lee, Sang-Guk Lee, S. Song, Soo-Youn Lee, H. Park. Recommendations for Liquid Chromatography-Mass Spectrometry in the Clinical Laboratory: Part II. Method Validation. 2020. https://doi.org/10.3343/lmo.2020.10.2.95
This study outlines essential validation guidelines for determining accuracy in clinical laboratory testing.
M. Hossen, Nee Edirisinghe, B. Fleiss, Rosita Zakaria. Basics of Method Evaluation in Clinical Laboratory Testing: A Mini-Review. 2024. https://doi.org/10.33176/aacb-24-00001
This review highlights that accuracy and method evaluation are essential components of clinical laboratory testing.
McInerney M, Hurley B, Barkow J, Menning K, Nicolace J, Schauer J, Van de Water J, Wassman ER. Analytical Validation of an ELISA Assay for Maternal Autoantibody-Related Autism.. 2026. https://doi.org/10.3390/diagnostics16111665
This paper reports on the analytical validation, sensitivity, and specificity of assays transferred to a clinical laboratory.
Tembo D, Kaphika JS, Ahmadu A, Alufandika L, Kalilangwe V, Kukacha C, Kaphika D, Lipenga FT, Machonjo M, Manda S, Masina M, Mchoma EC, Mnyanga AC, Moyo IM, Mutala FP, Mzumara P, Shani D, Selemani GP, Denis B. Implementing and Transitioning a Laboratory Quality Management System from ISO 15189:2012 to ISO 15189:2022: Experience from the Malawi-Liverpool Wellcome Research Programme, Blantyre.. 2026. https://doi.org/10.12688/wellcomeopenres.25356.2
This paper describes quality management systems and test method verification in clinical laboratories.
Kim H, Kim DY, Kim H. Analytical performance evaluation and method comparison of the 1copy BCR::ABL1 qPCR assay for monitoring chronic myeloid leukemia.. 2026. https://doi.org/10.1016/j.plabm.2026.e00538
This study evaluates the analytical performance and accuracy of a quantitative PCR assay for clinical monitoring.
The paper trail · every fact has a biography
Challenge the receipt
Citation formatting by citeproc-js (Frank Bennett) and the Citation Style Language project. Source and licenses.
Terms · Privacy · How verdicts work · Dispute this receipt