Having higher muscle mass influences blood pressure measurements
Current clinical and epidemiological evidence indicates that skeletal muscle mass is significantly associated with blood pressure measurements and arterial stiffness indicators.
The retrieved papers consistently demonstrate that skeletal muscle mass—whether high or low—correlates with or independently predicts blood pressure parameters and vascular stiffness markers (such as in large UK Biobank cohorts and smaller specialized studies). Therefore, the claim that higher muscle mass influences blood pressure measurements is supported.
Dongmin Lee, K. Byun, Moon-Hyon Hwang, Sewon Lee. Augmentation Index Is Inversely Associated with Skeletal Muscle Mass, Muscle Strength, and Anaerobic Power in Young Male Adults: A Preliminary Study. 2021. https://doi.org/10.3390/APP11073146
Augmentation index, a measure related to vascular properties, was found to be inversely associated with skeletal muscle mass in young male adults.
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Eduard Shantsila, Alena Shantsila, Matthew Sperrin, Zhuangzhi Gao, Yalin Zheng, Ian B. Wilkinson, Paul Leeson, Iain Buchan, Gregory Y.H. Lip. Higher skeletal muscle mass is associated with higher blood pressure and left ventricular mass. 2026. https://doi.org/10.1097/hjh.0000000000004375
Higher skeletal muscle mass was independently associated with higher systolic and diastolic blood pressure in a large cross-sectional and longitudinal cohort study.
Yuka Ohata, Mai Kabayama, M. Kido, K. Godai, M. Nagano, K. Kamide. PS-C25-10: ASSOCIATION BETWEEN SKELETAL MUSCLE MASS AND BLOOD PRESSURE DECLINE OVER A FIVE-YEAR PERIOD FOR COMMUNITY-DWELLING OLDER ADULTS. 2023. https://doi.org/10.1097/01.hjh.0000917060.11673.52
Lower skeletal muscle mass indices were found to be associated with systolic blood pressure decline in older adults over a 5-year period.
E Shantsila, A Shantsila, Z Gao, Y Zheng, G Y H Lip. High skeletal muscle mass is related to higher blood pressure and left ventricular mass irrespective of adiposity. 2025. https://doi.org/10.1093/eurjpc/zwaf236.117
Higher skeletal muscle mass showed an independent association with higher blood pressure and left ventricular mass even after accounting for adiposity.
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