Inflammation is a physiological immune response to tissue damage or infection
Inflammation functions as a fundamental physiological immune response initiated to combat infections and repair damaged tissues.
The retrieved literature consistently confirms that inflammation is a primary biological and immunological response triggered by tissue damage, pathogens, and various forms of stress or injury.
Linlin Chen, Huidan Deng, Hengmin Cui, Jing Fang, Zhicai Zuo, Junliang Deng, Yinglun Li, Xun Wang, Ling Zhao. Inflammatory responses and inflammation-associated diseases in organs. 2017. https://doi.org/10.18632/oncotarget.23208
Chen et al. (2017) explicitly state that inflammation is a biological response of the immune system triggered by factors including pathogens, damaged cells, and toxic compounds.
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Toshio Tanaka, Masashi Narazaki, T Kishimoto. IL-6 in Inflammation, Immunity, and Disease. 2014. https://doi.org/10.1101/cshperspect.a016295
IL-6 is described as being promptly produced in response to infections and tissue injuries, contributing to the inflammatory and immune response (Tanaka et al., 2014).
Kathryn E. Wellen, Gökhan S. Hotamışlıgil. Inflammation, stress, and diabetes. 2005. https://doi.org/10.1172/jci25102
Hotamisligil (2006) notes that the normal inflammatory response is a fundamental mechanism evolved to fight infection and heal tissue damage.
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