Astronauts on space missions have reported sleep disturbances and disruptions

C. Frantzidis, Christina Dimitriadou, Panteleimon Chriskos, S. Gilou, C. Plomariti, P. Gkivogkli, M. Karagianni, L. Konstantara, C. Nday, E. Kostakis, P. Bamidis, C. Kourtidou-Papadeli. Cortical connectivity analysis for assessing the impact of microgravity and the efficacy of reactive sledge jumps countermeasure to NREM 2 sleep. 2020. https://doi.org/10.1016/J.ACTAASTRO.2018.11.043

Examines how extreme environments like zero gravity impair sleep physiology and sleep quality.

E. Bersenev, Y. Ukraintseva, G. Kovrov, Y. Yakhya, G. Vassilieva, E. Tomilovskaya, I. Rukavishnikov, S. Posokhov, Artemiy V. Orlov, N. Osetsky, O. Orlov. Sleep in 21-Day Dry Immersion. Are Cardiovascular Adjustments Rapid Eye Movement Sleep-Dependent?. 2021. https://doi.org/10.3389/fphys.2021.749773

Notes that a decrease in sleep quality and duration during space missions has repeatedly been reported.

Luise Strauch, M. von der Wiesche, A. Noppe, E. Mulder, Iris Rieger, D. Aeschbach, E. Elmenhorst. Simulating microgravity with 60 days of 6 degree head-down tilt bed rest compromises sleep. 2024. https://doi.org/10.1038/s41526-024-00448-7

Demonstrates through simulated microgravity bed rest studies that astronauts often experience sleep loss and compromised sleep.

Zong H, Fei Y, Liu N. Circadian Disruption and Sleep Disorders in Astronauts: A Review of Multi-Disciplinary Interventions for Long-Duration Space Missions.. 2025. https://doi.org/10.3390/ijms26115179

Reviews how astronauts on long-duration missions face significant challenges from circadian rhythm disruptions and sleep disorders.