Human height is currently subject to natural selection
Recent genomic and anthropometric studies demonstrate that human height continues to be influenced by natural selection, with genetic variants affecting height showing clear signatures of selective pressures across populations.
The claim is specific and empirical. Papers [2] and [3] provide direct genomic evidence that human height is associated with genetic variants undergoing natural selection processes like positive and stabilizing selection. None of the papers refute this.
J. Gong, Huiru Sun, Kaiyuan Wang, Yanhui Zhao, Yechao Huang, Qinsheng Chen, H. Qiao, Yang Gao, Jialin Zhao, Y. Ling, R. Cao, Jingze Tan, Qi Wang, Yanyun Ma, Jing Li, Jingchun Luo, Sijia Wang, Jiucun Wang, Guoqing Zhang, Shuhua Xu, F. Qian, F. Zhou, Huiru Tang, Dali Li, F. Sedlazeck, Li Jin, Y. Guan, Shaohua Fan. Long-read sequencing of 945 Han individuals identifies structural variants associated with phenotypic diversity and disease susceptibility. 2025. https://doi.org/10.1038/s41467-025-56661-9
Long-read sequencing identifies structural variants associated with human height that exhibit signals of positive natural selection.
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Valeria Añorve-Garibay, Emilia Huerta-Sánchez, M. Sohail, Diego Ortega-Del Vecchyo. Natural selection acting on complex traits hampers the predictive accuracy of polygenic scores in ancient samples.. 2025. https://doi.org/10.1016/j.ajhg.2025.05.009
Analyses of ancient and modern human genomes demonstrate that natural selection, such as stabilizing and directional selection, actively shapes the temporal dynamics of height-associated genetic variants.
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