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the claim

The expected time for a neutral allele to reach frequency p1 from p0 can be calculated mathematically

the verdict
SUPPORTED
the evidence backs this
Recorded sources
4 sources for · 0 against

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Mathematical models in population genetics, such as diffusion approximations and coalescent theory, allow researchers to calculate the expected time for a neutral allele to reach a given frequency.

The analysis

The claim is specific, empirical, and well-established in evolutionary theory. Multiple provided papers discuss mathematical derivations for the time it takes for neutral alleles to reach specific frequencies or fixation using tools like diffusion approximations and coalescent theory.

Evidence for · 4
Recorded source metadata

D Waxman. Population Growth Enhances the Mean Fixation Time of Neutral Mutations and the Persistence of Neutral Variation. 2012. https://doi.org/10.1534/genetics.112.139220

Paper [1] discusses analytical expressions using diffusion approximation for the mean and variance of fixation times for neutral mutations.

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More for · 3
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TAI-HE FAN, SHUHAO SUN, PING-AN HE. THE TIME REQUIRED FOR ALLELE FREQUENCY CHANGE. 2017. https://doi.org/10.1017/s1446181117000050

Paper [7] examines expected times for allele frequency change under selection models using mathematical frameworks.

Recorded source metadata

Gili Greenbaum. Revisiting the time until fixation of a neutral mutant in a finite population - A coalescent theory approach.. 2015. https://doi.org/10.1016/j.jtbi.2015.05.019

Paper [9] derives analytic formulations of genetic drift and fixation time scales of neutral mutations using diffusion approximations and coalescent theory.

Recorded source metadata

Luca Ferretti, Paolo Ribeca. Allelic Entropy and Times until Loss or Fixation of Neutral Polymorphisms.. 2023. https://doi.org/10.3390/genes14091751

Paper [11] uses the diffusion approximation of the neutral Wright-Fisher model to relate the expected time until fixation of a neutral allele to population entropy.

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first checked01 Aug 2026
judged → SUPPORTED · 8201 Aug 2026
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