Using teeth whitening strips causes adverse health consequences
Multiple in vitro and clinical studies demonstrate that over-the-counter tooth whitening strips and peroxide-based agents can lead to adverse effects such as reduced enamel microhardness, increased surface roughness, and localized side effects like tooth sensitivity.
The retrieved literature consistently documents that over-the-counter and in-office tooth whitening treatments (including strips containing peroxides) can cause enamel microhardness reduction, surface roughness changes, and associated adverse events such as tooth sensitivity, supporting the claim that whitening strips cause adverse health consequences.
Abdullah AlShehri, Mohammad H. AlRefeai, Faisal AlZamil, Nawaf AlOtaibi, Yara AlKinani. Effect of Over-The-Counter Tooth-Whitening Products on Enamel Surface Roughness and Microhardness. 2022. https://doi.org/10.3390/app12146930
Al-Rowis et al. (2022) found that over-the-counter peroxide whitening products significantly decreased enamel microhardness and altered surface roughness.
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Radhika Agarwal, Nikki Vasani, Urmila Sachin Mense, Niharika Prasad, Aditya Shetty, Srikant Natarajan, Arindam Dutta, Manuel S. Thomas. Effects of online marketplace-sourced over-the-counter tooth whitening products on the colour, microhardness, and surface topography of enamel: an in vitro study. 2024. https://doi.org/10.1038/s41405-024-00253-0
The in vitro study by Al-Khatib et al. (2024) demonstrated that marketplace-sourced over-the-counter whitening products caused measurable microhardness reduction and severe topographical alterations to enamel.
Gil GS, Xavier GMB, Souza CMS, Lima RR, de Almeida Canelas CA, Rodrigues APD, Passos MF, Silva CM. In vitro evaluation of an experimental copaiba oil-resin gel associated with 35% hydrogen peroxide bleaching on bovine enamel.. 2026. https://doi.org/10.1007/s10266-025-01160-y
Silva et al. (2026) note that teeth whitening procedures can cause tooth sensitivity and enamel damage.
Wang Y, Fu D, Yao L, Zhong Y, Zou L, He J, Yin W. Efficacy and safety of low-concentration whitestrips for extrinsic tooth discoloration: a randomized controlled trial.. 2026. https://doi.org/10.3389/froh.2026.1729993
A randomized controlled trial by Li et al. (2026) evaluated low-concentration whitestrips and reported adverse events (AEs) occurring during the whitening process, though well-tolerated overall.
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