Maternal antibodies in breast milk survive infant digestion to provide immunity.
Maternal antibodies present in breast milk, particularly secretory IgA, possess mechanisms that allow them to partially survive the harsh environment of the infant gastrointestinal tract to provide mucosal immunity.
The claim is specific, testable, and supported by immunological findings showing that breast milk antibodies like secretory IgA resist parts of infant digestion to protect against pathogens.
Myrtani Pieri, Vicky Nicolaidou, Irene Paphiti, Spyros Pipis, Kyriacos Felekkis, Christos Papaneophytou. Survival of vaccine-induced human milk SARS-CoV-2 IgG and IgA immunoglobulins across simulated human infant gastrointestinal digestion. 2021. https://doi.org/10.1101/2021.06.17.21259021
Paper 1 demonstrates that certain vaccine-induced antibodies (such as IgA) in human milk can partially resist the gastric phase of infant digestion.
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A E Wold, I Adlerberth. Breast feeding and the intestinal microflora of the infant--implications for protection against infectious diseases.. 2000. https://doi.org/10.1007/0-306-46830-1_7
Paper 7 notes that secretory IgA in breast milk protects infants by coating intestinal bacteria and blocking interactions without being completely destroyed.
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