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the claim
XYY syndrome is caused by nondisjunction during paternal meiosis II
the verdict
REFUTED
the evidence says no
refutedsupported
the weight of evidence
2 sources for · 1 against

While multiple medical references state that XYY syndrome is caused by nondisjunction during paternal meiosis II, other sources attribute it to paternal meiosis I or postzygotic errors, making the specific meiotic stage contested in literature.

Evidence for · 2
Churchill Livingstone: Principles and practice of medical genetics
1983 · cited by 0
States the likely explanation of 47,XYY is non-disjunction at paternal meiosis II.
Evidence against · 1
Double Aneuploidy of Down Syndrome (Trisomy 21) and Jacobs Syndrome (Trisomy XYY) with Complete Tracheal Rings Deformity: Case Report and Literature Review
2023 · cited by 3
Claims trisomy XYY results from nondisjunction during paternal spermatocyte meiosis-I, contradicting meiosis II.
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The analysis

Judged against the evidence record for claims of this kind.

More for · 1
Churchill Livingstone: Principles and practice of medical genetics
1990 · cited by 0
States the likely explanation of 47,XYY is non-disjunction at paternal meiosis II.
Everything we examined (16) — 11 independent sources
This check searched the claim as stated. It did not run a separate search for evidence against it.
  1. Wikipedia: XYY syndromereferencesame source L1no side takennot shown: read and judged not to bear on this claim
  2. Wikipedia: Meiosisreferencesame source L1no side takennot shown: read and judged not to bear on this claim
  3. Book: Encyclopedia of Molecular Mechanisms of Diseasereferencesupportsnot shown: a book pointing against the verdict the rest of the record settles
  4. Book: Thompson & Thompson Genetics in Medicine E-Bookreferencesame source L3supportsnot shown: read and judged not to bear on this claim
  5. Book: Brenner's Encyclopedia of Geneticsreferenceno side takennot shown: read and judged not to bear on this claim
  6. Book: Geneticsreferencesupportsnot shown: a book pointing against the verdict the rest of the record settles
  7. Saunders: Genetics in obstetrics and gynecologyreferencesame source L6no side takennot shown: read and judged not to bear on this claim
  8. Saunders: Genetics in obstetrics & gynecologyreferencesame source L6no side takennot shown: read and judged not to bear on this claim
  9. Churchill Livingstone: Principles and practice of medical geneticsreferencesame source L7supports
  10. A.R. Liss: Chromosomal variation in man : a catalog of chromosomal variants and anomaliesreferenceno side takennot shown: read and judged not to bear on this claim
  11. Churchill Livingstone: Principles and practice of medical geneticsreferencesame source L7supports
  12. Humana Press: Principles of molecular medicinereferenceno side takennot shown: read and judged not to bear on this claim
  13. Elsevier: The chromosomes in human cancer and leukemiareferencesame source L3no side takennot shown: read and judged not to bear on this claim
  14. ELSEVIER: JAYPEE (Old) Williams Textbook of ENDOCRINOLOGYreferencesame source L3no side takennot shown: read and judged not to bear on this claim
  15. OpenAIRE: Commentary: Unravelling the effects of additional sex chromosomes on cognition and communication – reflections on Lee et al. (2012)peer-reviewedno side takennot shown: read and judged not to bear on this claim
  16. Double Aneuploidy of Down Syndrome (Trisomy 21) and Jacobs Syndrome (Trisomy XYY) with Complete Tracheal Rings Deformity: Case Report and Literature Reviewpeer-reviewedrefutes
The paper trail · every fact has a biography
first checked06 Aug 2026
judged → REFUTED · 4406 Aug 2026
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