While skin prick tests are routinely used in clinical evaluations, multiple studies find them prone to false positives and limited accuracy, necessitating oral food challenges as the definitive diagnostic standard.
Skin prick tests have limited accuracy and high false positive rates, while oral food challenges serve as the definitive diagnostic standard.
The retrieved literature extensively evaluates the diagnostic utility of skin prick tests and oral food challenges (OFCs). While paper [5] uses both tests in an intervention cohort, numerous papers ([0], [6], [7], [8], [11]) explicitly state that skin prick tests have limited accuracy, high false-positive rates, or are insufficient on their own, and that OFCs remain the necessary gold standard. Thus, the claim that these tests reliably diagnose food allergies is contested by evidence showing skin prick tests alone are unreliable and require OFC confirmation.