Sertraline administration impacts white blood cell counts and immunological parameters

the verdict

SUPPORTED

the evidence backs this

Recorded sources

2 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that Sertraline administration impacts white blood cell counts and immunological parameters?

Yes. Clinical evidence indicates that the administration of selective serotonin reuptake inhibitors, such as sertraline-related compounds, impacts immunological parameters and white blood cell counts.

Verdict: SUPPORTED · 2 sources for, 0 against · Last checked 4 Aug 2026

The analysis

The claim specifically asserts that sertraline administration impacts white blood cell counts and immunological parameters. Paper [1] demonstrates that selective serotonin reuptake inhibitors (SSRIs) significantly reduce white blood cell counts and inflammatory markers. Paper [7] confirms the general immunomodulatory effects of SSRIs. No papers refute the claim, leading to a SUPPORTED verdict.

Evidence for · 2

Effects of fluoxetine and escitalopram on C-reactive protein in patients of depression

2011

Demonstrates that selective serotonin reuptake inhibitors like fluoxetine and escitalopram significantly reduce white blood cell counts and inflammatory markers in depressed patients.

Get citation

Chavda, N., Kantharia, N., & Jaykaran (2011). Effects of fluoxetine and escitalopram on C-reactive protein in patients of depression. doi.org. https://doi.org/10.4103/0976-500X.77091

See more details

More for · 1

The potential action of SSRIs in the treatment of skin diseases including atopic dermatitis and slow-healing wounds.

2022

Highlights the broader immunomodulatory and antimicrobial properties of selective serotonin reuptake inhibitors.

Get citation

A, K. & M, S. (2022). The potential action of SSRIs in the treatment of skin diseases including atopic dermatitis and slow-healing wounds.. doi.org. https://doi.org/10.1007/s43440-022-00423-7

Related receipts

Is it true that testosterone therapy increases red blood cell count in men? SUPPORTED related question, same topic
Is it true that white blood cells do not mount an immune response against human sperm cells? REFUTED related question, same topic

Receipt History

first checked04 Aug 2026

judged → SUPPORTED · 8604 Aug 2026

Anyone with this link can read the claim and its public receipt, including any personal information in that text. Open permanent receipt.

Check your own claim

Challenge the receipt

I have a source that contradicts this verdict I have a source that supports it No source: request a receipt review Requests are recorded for review. This does not start an automatic check or guarantee a response time.

See the evidence timeline

Citation formatting by citeproc-js (Frank Bennett) and the Citation Style Language project. Source and licenses.

This receipt is an automated verdict against our published method · not an opinion about any author or publication.
Terms · Privacy · How verdicts work