Replacing sodium chloride with potassium chloride in the diet effectively reduces both systolic and diastolic blood pressure, as supported by multiple randomized controlled trials, systematic reviews, and meta-analyses.
The retrieved papers consistently demonstrate that substituting sodium chloride with potassium chloride (low-sodium/potassium-enriched salt substitutes) leads to significant reductions in blood pressure across diverse populations, including hypertensive and resistant-hypertension patients. The evidence base comprises systematic reviews, meta-analyses, and clinical trials that uniformly support the claim without any contradictory studies in the provided set.