Physical interactions refer to direct binding between protein molecules, whereas genetic interactions refer to functional dependencies where a mutation in one gene affects the phenotypic outcome of another, making them distinct biological phenomena that are frequently studied together.
The distinction between physical protein-protein interactions (such as structural binding or proximity) and genetic interactions (such as synthetic lethality or epistatic effects) is a fundamental, textbook concept in molecular biology. Therefore, it is common knowledge that does not require direct citation of papers to validate.