Papaya leaf extract increases platelet count in dengue patients
Is it true that Papaya leaf extract increases platelet count in dengue patients?
Yes. Multiple clinical trials, systematic reviews, and meta-analyses support the finding that Carica papaya leaf extract helps increase platelet counts in patients suffering from dengue fever.
Verdict: SUPPORTED · 6 sources for, 0 against · Last checked
The retrieved literature contains robust systematic reviews, meta-analyses, and randomized controlled trials (both adult and pediatric) showing that Carica papaya leaf extract significantly increases platelet counts and alleviates thrombocytopenia in dengue patients. None of the provided papers refute this claim.
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Charan, J., Saxena, D., Goyal, J., & Yasobant, S. (2016). Efficacy and safety of Carica papaya leaf extract in the dengue: A systematic review and meta-analysis. doi.org. https://doi.org/10.4103/2229-516X.192596
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Srikanth, B., Reddy, L., Biradar, S., Shamanna, M., Mariguddi, D. D., & Krishnakumar, M. (2019). An open-label, randomized prospective study to evaluate the efficacy and safety of Carica papaya leaf extract for thrombocytopenia associated with dengue fever in pediatric subjects. doi.org. https://doi.org/10.2147/PHMT.S176712
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S, M., ZW, L., T, T., R, R., PŁ, K., J, L., A, B., M, A., M, I., & RM, A. (2022). Delving into the Therapeutic Potential of <i>Carica papaya</i> Leaf against Thrombocytopenia.. doi.org. https://doi.org/10.3390/molecules27092760
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MMR, S., F, K., & IN, M. (2021). Dengue Fever: Therapeutic Potential of <i>Carica papaya</i> L. Leaves.. doi.org. https://doi.org/10.3389/fphar.2021.610912
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BP, T., NB, A., SB, M., TYC, T., MRB, M. A. R., AB, A., & AFB, S. M. (2022). <i>Carica papaya</i> Leaf Juice for Dengue: A Scoping Review.. doi.org. https://doi.org/10.3390/nu14081584
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K., V., M., S. R., & R., H. B. (2018). Role of Carica papaya leaf extract tablets/capsules on platelet counts in cases of dengue thrombocytopenia. doi.org. https://doi.org/10.18203/2349-3933.ijam20182500
What does the evidence say?
The retrieved literature contains robust systematic reviews, meta-analyses, and randomized controlled trials (both adult and pediatric) showing that Carica papaya leaf extract significantly increases platelet counts and alleviates thrombocytopenia in dengue patients. None of the provided papers refute this claim.
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