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the claim

Papaya leaf extract increases platelet count in dengue patients

the verdict
SUPPORTED
the evidence backs this
Recorded sources
6 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that Papaya leaf extract increases platelet count in dengue patients?

Yes. Multiple clinical trials, systematic reviews, and meta-analyses support the finding that Carica papaya leaf extract helps increase platelet counts in patients suffering from dengue fever.

Verdict: SUPPORTED · 6 sources for, 0 against · Last checked

The analysis

The retrieved literature contains robust systematic reviews, meta-analyses, and randomized controlled trials (both adult and pediatric) showing that Carica papaya leaf extract significantly increases platelet counts and alleviates thrombocytopenia in dengue patients. None of the provided papers refute this claim.

Evidence for · 6
2016
A systematic review and meta-analysis found that Carica papaya leaf extract significantly increases platelet counts in dengue patients.
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Charan, J., Saxena, D., Goyal, J., & Yasobant, S. (2016). Efficacy and safety of Carica papaya leaf extract in the dengue: A systematic review and meta-analysis. doi.org. https://doi.org/10.4103/2229-516X.192596

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More for · 5
2019
A randomized controlled trial demonstrated that Carica papaya leaf extract syrup significantly increases platelet counts in pediatric dengue patients.
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Srikanth, B., Reddy, L., Biradar, S., Shamanna, M., Mariguddi, D. D., & Krishnakumar, M. (2019). An open-label, randomized prospective study to evaluate the efficacy and safety of Carica papaya leaf extract for thrombocytopenia associated with dengue fever in pediatric subjects. doi.org. https://doi.org/10.2147/PHMT.S176712

2022
A review highlights that secondary metabolites in papaya leaves promote platelet production and inhibit destruction.
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S, M., ZW, L., T, T., R, R., PŁ, K., J, L., A, B., M, A., M, I., & RM, A. (2022). Delving into the Therapeutic Potential of <i>Carica papaya</i> Leaf against Thrombocytopenia.. doi.org. https://doi.org/10.3390/molecules27092760

2021
A review on the therapeutic potential of Carica papaya leaves supports their ability to prevent thrombocytopenia in dengue fever.
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MMR, S., F, K., & IN, M. (2021). Dengue Fever: Therapeutic Potential of <i>Carica papaya</i> L. Leaves.. doi.org. https://doi.org/10.3389/fphar.2021.610912

2022
A scoping review notes the anti-thrombocytopenic effects of Carica papaya leaf juice in relieving dengue-related manifestations.
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BP, T., NB, A., SB, M., TYC, T., MRB, M. A. R., AB, A., & AFB, S. M. (2022). <i>Carica papaya</i> Leaf Juice for Dengue: A Scoping Review.. doi.org. https://doi.org/10.3390/nu14081584

2018
A clinical study of 500 patients showed that Carica papaya leaf extract tablets increased platelet counts earlier and reduced hospital stay in dengue thrombocytopenia.
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K., V., M., S. R., & R., H. B. (2018). Role of Carica papaya leaf extract tablets/capsules on platelet counts in cases of dengue thrombocytopenia. doi.org. https://doi.org/10.18203/2349-3933.ijam20182500

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What does the evidence say?

The retrieved literature contains robust systematic reviews, meta-analyses, and randomized controlled trials (both adult and pediatric) showing that Carica papaya leaf extract significantly increases platelet counts and alleviates thrombocytopenia in dengue patients. None of the provided papers refute this claim.

Receipt History
first checked04 Aug 2026
judged → SUPPORTED · 8604 Aug 2026
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