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the claim
Neurons possess mechanisms to temporarily increase membrane resistance
the verdict
SUPPORTED
the evidence backs this
refutedsupported
the weight of evidence
2 sources for · 0 against

Neurons utilize various regulatory mechanisms, such as ion channel modulation during hypoxic events or changes in ionic currents, to temporarily alter their membrane resistance.

Evidence for · 2
Anti-hypoxic effect of interleukin-10 in hippocampal neurons is mediated by modulation of TASK-1 and TASK-3 channels activity.
2022 · cited by 6
The paper demonstrates that brief hypoxic episodes can cause a significant increase in neuronal membrane input resistance.
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The analysis

The claim states that neurons possess mechanisms to temporarily increase membrane resistance. Multiple papers (such as [2], which notes that hypoxia and cytokine modulation can increase input resistance, and [3], which discusses how reducing h-current increases membrane input resistance) provide direct evidence supporting this physiological capability.

More for · 1
H-current modulation of cortical Up and Down states
2024 · cited by 3
The paper shows that reducing h-current leads to an increased input resistance in neurons, modulating network activity.
The paper trail · every fact has a biography
first checked04 Aug 2026
judged → SUPPORTED · 8004 Aug 2026
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