While neurons possess powerful homeostatic mechanisms to regulate and stabilize their firing rates around target ranges over long periods, in vivo evidence shows their firing rates are continuously dynamic and fluctuate rather than maintaining a strict constant minimum.
Neurons use homeostatic mechanisms to regulate and stabilize their firing rates around target ranges over long periods.
The claim states that neurons maintain a specific *minimum constant* firing rate. The retrieved papers discuss 'firing rate homeostasis' (papers [0], [4], [7]), which means neurons regulate activity toward a baseline or set point over time, but they do so dynamically rather than maintaining a static, constant rate. In fact, papers [2] and [9] explicitly demonstrate that firing rates naturally fluctuate significantly in vivo based on stimuli, state changes, and task demands. Thus, while homeostatic regulation exists, the idea of a fixed constant rate is contested by continuous natural variability.