trustme.bro/r/…
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the claim
Mederma is effective for scar removal
the verdict
CONTESTED
the evidence cuts both ways
confidence 20/100

The efficacy of Mederma and its active ingredient, onion extract, for scar removal is contested, with clinical trials and reviews showing mixed results compared to standard silicone therapies and controls.

The evidence we hold leans leans refuted

How this was weighed

official record 3x · fact-check 2x · hedged 1x · crowd & reference 1x

  • Evaluating efficacy and safety of the topical silicone gel c · peer-reviewed · supports · weight 1.05 · 2021
  • Evidence-Based Topical Therapy for Facial Scars in Diverse S · peer-reviewed · supports · weight 1 · 2025
  • Comparison of the Effectiveness of Onion Extract, Topical St · peer-reviewed · refutes · weight 1.05 · 2020
  • Pediatric Facial Lacerations: Evidence-Based Over-the-Counte · peer-reviewed · refutes · weight 1 · 2025
  • Strategies to improve facial scars following Mohs micrograph · peer-reviewed · refutes · weight 1 · 2025
Evidence for · 2
Evaluating efficacy and safety of the topical silicone gel containing onion extract in the treatment of post‐cesarean surgical scars
2021 · cited by 5
This study suggests that silicone gel containing onion extract improves scar erythema compared to control.
Evidence against · 3
Comparison of the Effectiveness of Onion Extract, Topical Steroid, and Petrolatum Emollient in Cosmetic Appearance of Upper Blepharoplasty Scar
2020 · cited by 9
This trial found no significant differences in scar appearance between onion extract, topical steroids, and petrolatum emollient.
See more details
More for · 1
Evidence-Based Topical Therapy for Facial Scars in Diverse Skin Types.
2025 · cited by 0
This review lists onion extract among agents supported for scar modulation in a phase-specific approach.
More against · 2
Pediatric Facial Lacerations: Evidence-Based Over-the-Counter Wound Care and Scar Prevention for Clinicians and Caregivers.
2025 · cited by 0
This review notes that over-the-counter products like onion extract offer minimal benefit compared to silicone-based therapies.
Strategies to improve facial scars following Mohs micrographic surgery.
2025 · cited by 0
This review explicitly states that treatments like topical onion extract lack evidence of efficacy.
The paper trail · every fact has a biography
first checked02 Aug 2026
judged → CONTESTED · 2002 Aug 2026
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