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the claim
Mean diffusivity provides information about the connectivity of cortical areas.
the verdict
SUPPORTED
the evidence backs this
Recorded sources
4 sources for · 0 against
Is it true that mean diffusivity provides information about the connectivity of cortical areas?
Yes. Multiple diffusion tensor imaging studies demonstrate that mean diffusivity metrics provide valuable information regarding the microstructural integrity and connectivity of cortical and subcortical areas.
Verdict: SUPPORTED · 4 sources for, 0 against · Last checked
The analysis
The retrieved literature consistently utilizes diffusion tensor imaging metrics, particularly mean diffusivity (MD), to investigate structural connectivity and microstructural properties between and within cortical areas. Papers [0], [6], [7], and [10] directly connect MD measurements to tract-based connectivity or structural networks. No papers refute the claim.
Evidence for · 4
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Hughes, E., Bond, J., Svrckova, P., Makropoulos, A., Ball, G., Sharp, D., Edwards, A., Hajnal, J. V., & Counsell, S. (2012). Regional changes in thalamic shape and volume with increasing age. doi.org. https://doi.org/10.1016/j.neuroimage.2012.07.043
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More for · 3
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Jonkman, L., Fathy, Y. Y., Berendse, H., Schoonheim, M., & Berg, W. V. D. v. d. (2021). Structural network topology and microstructural alterations of the anterior insula associate with cognitive and affective impairment in Parkinson’s disease. doi.org. https://doi.org/10.1038/s41598-021-95638-8
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Gao, Y., Schilling, K., Stepniewska, I., Plassard, A., Choe, A. S., Li, X., Landman, B., & Anderson, A. (2017). Tests of cortical parcellation based on white matter connectivity using Diffusion Tensor Imaging. doi.org. https://doi.org/10.1016/j.neuroimage.2017.02.048
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Abdelnour, F., Raj, A., Devinsky, O., & Thesen, T. (2016). Network Analysis on Predicting Mean Diffusivity Change at Group Level in Temporal Lobe Epilepsy. doi.org. https://doi.org/10.1089/brain.2015.0381
Receipt History
first checked04 Aug 2026
judged → SUPPORTED · 8804 Aug 2026
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