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the claim

Low calcium levels directly cause nerve hyperexcitation

the verdict
SUPPORTED
the evidence backs this
Recorded sources
2 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that low calcium levels directly cause nerve hyperexcitation?

Yes. Low extracellular calcium levels reduce the threshold for depolarization, directly increasing neuromuscular excitability and leading to clinical signs such as tetany and seizures.

Verdict: SUPPORTED · 2 sources for, 0 against · Last checked

The analysis

The claim is specific and physiologically well-established: extracellular calcium stabilizes voltage-gated sodium channels on nerve membranes. When calcium levels drop (hypocalcemia), these channels open more easily, leading to nerve hyperexcitation. Papers [7] and [8] directly support this physiological relationship, while the other retrieved papers address unrelated topics such as autism, magnesium, or specific channelopathies.

Evidence for · 2
A Quick Reference on Hypocalcemia.
2026
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Parker, V. J. & Chew, D. J. (2026). A Quick Reference on Hypocalcemia.. doi.org. https://doi.org/10.1016/j.cvsm.2025.09.013

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More for · 1
Hypocalcemia in the newborn.
2010
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Jain, A., Agarwal, R., Sankar, M. J., Deorari, A., & Paul, V. K. (2010). Hypocalcemia in the newborn.. doi.org. https://doi.org/10.1007/s12098-010-0176-0

Receipt History
first checked31 Jul 2026
judged → SUPPORTED · 7531 Jul 2026
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