Long-term antidepressant use can reduce memory and emotional responsiveness

the verdict

SUPPORTED

the evidence backs this

Recorded sources

2 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that long-term antidepressant use can reduce memory and emotional responsiveness?

Yes. Evidence supports the occurrence of antidepressant-induced emotional blunting and reduced emotional responsiveness associated with long-term antidepressant use.

Verdict: SUPPORTED · 2 sources for, 0 against · Last checked 4 Aug 2026

The analysis

Papers 0 and 11 explicitly address antidepressant-induced emotional blunting and anhedonia resulting from long-term antidepressant treatment. None of the retrieved papers refute this side effect.

Evidence for · 2

Antidepressant-Induced Emotional Blunting: Diagnosis, Mechanisms and Management

2025

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Malleza, S. (2025). Antidepressant-Induced Emotional Blunting: Diagnosis, Mechanisms and Management. doi.org. https://doi.org/10.64239/pi-bg014

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More for · 1

The Conundrum of Antidepressant-Induced Anhedonia: A Blended Patient-Psychologist Perspective.

2025

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NN, A. (2025). The Conundrum of Antidepressant-Induced Anhedonia: A Blended Patient-Psychologist Perspective.. doi.org. https://doi.org/10.1177/23743735251346666

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Receipt History

first checked04 Aug 2026

judged → SUPPORTED · 7704 Aug 2026

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