Clinical evidence confirms that irregular menstrual cycles are fundamentally driven by underlying hormonal imbalances and endocrine disorders such as polycystic ovary syndrome.
The claim is a specific, empirical statement about the medical pathophysiology of irregular menstrual cycles. Retrieved papers such as [1], [4], [10], and [11] explicitly discuss how hormonal imbalances, endocrine disorders (like PCOS), and metabolic dysfunctions directly cause menstrual irregularities and abnormal uterine bleeding. The evidence strongly supports the claim, yielding a verdict of SUPPORTED.