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the claim
Inward rectifier potassium channels regulate cardiac action potentials
the verdict
SUPPORTED
the evidence backs this
refutedsupported
the weight of evidence
3 sources for · 0 against

Inward rectifier potassium channels play a critical role in regulating the resting membrane potential, action potential duration, and overall electrophysiological stability of cardiac tissue.

Evidence for · 3
2009 · cited by 37
This paper demonstrates that inward rectifier potassium currents (IK1) are crucial for regulating cardiac excitability, action potential duration, and the stability of reentry during ventricular fibrillation.
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The analysis

The retrieved literature consistently supports the claim that inward rectifier potassium channels regulate cardiac action potentials. Papers 0, 1, and 9 specifically detail how these channels govern resting membrane potential, action potential duration, and cardiac excitability. No retrieved papers contradict this well-established physiological principle.

More for · 2
2020 · cited by 8
This study establishes that Kir2.1 inward rectifier potassium channels are key regulators of the resting membrane potential and ventricular action potential duration in the human heart.
2026 · cited by 0
This review highlights that potassium currents, including inward-rectifier channels, play a vital role in regulating cardiac action potentials, refractory periods, and preventing arrhythmogenesis.
The paper trail · every fact has a biography
first checked04 Aug 2026
judged → SUPPORTED · 8504 Aug 2026
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