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the claim

HindII was the first restriction endonuclease to be extracted

the verdict
SUPPORTED
the evidence backs this
Recorded sources
2 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that HindII was the first restriction endonuclease to be extracted?

Yes. Evidence establishes that HindII (originally called endonuclease R) was the first restriction endonuclease to be isolated and characterized.

Verdict: SUPPORTED · 2 sources for, 0 against · Last checked

How claims like this are judged

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Evidence for · 2
States Smith and Wilcox reported the isolation and characterization of the first restriction enzyme (endonuclease R, later HindII).
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nature.com: (untitled). (n.d.). nature.com. http://nature.com/articles/miledna04.pdf

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More for · 1
Notes that the first restriction endonuclease, HindII, was isolated and characterized.
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biology.stackexchange.com: Which was the first restriction endonuclease to be isolated?. (n.d.). biology.stackexchange.com. https://biology.stackexchange.com/questions/112586/which-was-the-first-restriction-endonuclease-to-be-isolated

Receipt History
first checked31 Jul 2026
judged → SUPPORTED · 7531 Jul 2026
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