High-dose potassium supplementation without medical supervision can cause hyperkalemia.

The claim states that high-dose potassium supplementation without medical supervision can cause hyperkalemia. This is a well-established physiological fact governed by electrolyte homeostasis and kidney function, making it common knowledge. Paper [11] supports this by showing potassium supplementation increases plasma potassium levels in certain experimental conditions, but none of the retrieved papers directly evaluate unsupervised human high-dose potassium supplementation causing hyperkalemia as their primary focus. Thus, the verdict is COMMON_KNOWLEDGE, with supportive biochemical evidence cited where applicable.