High concentrations of hydrogen peroxide inhibit or denature catalase

the verdict

SUPPORTED

the evidence backs this

Recorded sources

2 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that high concentrations of hydrogen peroxide inhibit or denature catalase?

Yes. High concentrations of hydrogen peroxide can inhibit or denature catalase, as supported by classical and kinetic studies demonstrating substrate-induced inactivation at elevated peroxide levels.

Verdict: SUPPORTED · 2 sources for, 0 against · Last checked 4 Aug 2026

The analysis

The retrieved literature includes foundational kinetic studies (such as papers [1] and [4]) showing that elevated concentrations of hydrogen peroxide lead to the formation of inactive enzyme species and increased inactivation rates (substrate inhibition/denaturation). Therefore, the claim is well supported by the provided evidence.

Evidence for · 2

The catalase–hydrogen peroxide system. Kinetics of catalatic action at high substrate concentrations

1968

Demonstrates that high substrate concentrations of hydrogen peroxide lead to the formation of inactive catalase species such as Compound II.

Get citation

Jones, P. & Suggett, A. (1968). The catalase–hydrogen peroxide system. Kinetics of catalatic action at high substrate concentrations. doi.org. https://doi.org/10.1042/bj1100617

See more details

More for · 1

THE KINETICS OF THE DECOMPOSITION OF PEROXIDE BY CATALASE

1925

Shows that in very high concentrations of peroxide, the spontaneous inactivation rate of catalase increases.

Get citation

Northrop, J. (1925). THE KINETICS OF THE DECOMPOSITION OF PEROXIDE BY CATALASE. doi.org. https://doi.org/10.1085/jgp.7.3.373

Related receipts

Is it true that hydrogen peroxide decomposes into water and oxygen? SUPPORTED related question, same topic
Is it true that hydrogen peroxide effectively whitens teeth? SUPPORTED related question, same topic
Is it true that hydrogen peroxide undergoes disproportionation reactions? SUPPORTED related question, same topic
Is it true that drinking hydrogen peroxide therapy is safe for human consumption? REFUTED related question, same topic

Receipt History

first checked04 Aug 2026

judged → SUPPORTED · 8604 Aug 2026

Anyone with this link can read the claim and its public receipt, including any personal information in that text. Open permanent receipt.

Check your own claim

Challenge the receipt

I have a source that contradicts this verdict I have a source that supports it No source: request a receipt review Requests are recorded for review. This does not start an automatic check or guarantee a response time.

See the evidence timeline

Citation formatting by citeproc-js (Frank Bennett) and the Citation Style Language project. Source and licenses.

This receipt is an automated verdict against our published method · not an opinion about any author or publication.
Terms · Privacy · How verdicts work