Multiple clinical and epidemiological studies demonstrate that Gram-negative bacteria frequently present with severe multidrug-resistant strains, including ESBL producers and carbapenem-resistant organisms.
The retrieved papers consistently document high levels of multidrug resistance, carbapenemase production, and extended-spectrum beta-lactamase (ESBL) activity among various Gram-negative pathogens. There are no papers contradicting the premise that Gram-negative bacteria are heavily associated with highly resistant strains, making SUPPORTED the appropriate verdict.