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the claim
Golden Gate assembly enables the joining of small DNA parts.
the verdict
SUPPORTED
the evidence backs this
refutedsupported
the weight of evidence
4 sources for · 0 against

Multiple studies demonstrate that Golden Gate assembly effectively joins small DNA parts, fragments, and modules into larger constructs in a single reaction.

Evidence for · 4
2020 · cited by 135
Golden Gate cloning is described as a method used for the assembly of multiple DNA fragments in a defined linear order using a one-pot procedure.
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The analysis

The retrieved papers consistently describe and utilize Golden Gate cloning/assembly as a standard technique for joining multiple DNA parts and fragments. Papers 0, 5, 7, and 11 explicitly confirm this capability across various applications in synthetic biology.

More for · 3
2026 · cited by 3
CyanoConstruct utilizes a single Golden Gate reaction to assemble multi-gene expression plasmids from individual parts.
2026 · cited by 1
Slowpoke automates Golden Gate-based cloning workflows for standardizing DNA assembly in synthetic biology.
2026 · cited by 0
Golden Gate vector assembly is integrated into protocols for generating targeted constructs in plant functional genomics.
Everything we examined (12)
  1. Synthetic DNA Assembly Using Golden Gate Cloning and the Hierarchical Modular Cloning Pipelinepeer-reviewedsupports
  2. Practical Approaches for Cryo-FIB Milling and Applications for Cellular Cryo-Electron Tomography.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  3. CRISPR-GPT for agentic automation of gene-editing experiments.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  4. Potential for Applying Continuous Directed Evolution to Plant Enzymes: An Exploratory Study.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  5. A game of tag: A review of protein tags for the successful detection, purification and fluorescence labelling of proteins expressed in microalgae.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  6. CyanoConstruct: simple platform for cyanobacterial expression construct assembly and translational tuning.peer-reviewedsupports
  7. Precise kilobase-scale genomic insertions in mammalian cells using PASTE.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  8. Slowpoke: An Automated Golden Gate Cloning Workflow for Opentrons OT-2 and Flex.peer-reviewedsupports
  9. Multichannel genomic recording of biological information with ENGRAM.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  10. tRNA-based polycistronic CRISPR/Cas9 system boosts efficiency of multi-gene deletion in the moss Physcomitrella.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  11. Getting the Right Clones in an Automated Manner: An Alternative to Sophisticated Colony-Picking Robotics.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  12. Genome editing and regeneration pipeline for engineering disease resistance in tomato using CRISPR/Cas9.peer-reviewedsupports
The paper trail · every fact has a biography
first checked05 Aug 2026
judged → SUPPORTED · 8805 Aug 2026
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