Substantial scientific literature establishes that environmental factors such as diet, lifestyle, and toxins alter human gene expression through epigenetic mechanisms including DNA methylation and histone modification.
The retrieved papers overwhelmingly support the claim that environmental factors alter gene expression through epigenetic mechanisms. Multiple reviews and empirical studies (e.g., [0], [1], [2], [3], [5], [6], [7], [8], [10]) document how dietary components, stress, lifestyle, and other environmental exposures induce epigenetic modifications (such as DNA methylation, histone modifications, and non-coding RNA regulation) that impact gene expression and disease risk. There are no papers refuting this well-established biological principle.