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the claim

Double spike isotopic standards are suitable for quantification by isotope dilution mass spectrometry

the verdict
SUPPORTED
the evidence backs this
Recorded sources
2 sources for · 0 against

Counts group repeated records of the same source within each side. They do not measure evidence strength or source independence.

Is it true that double spike isotopic standards are suitable for quantification by isotope dilution mass spectrometry?

Yes. Double spike isotopic standards and associated isotope dilution mass spectrometry methods are demonstrated to be accurate and suitable for precise quantitative chemical analysis.

Verdict: SUPPORTED · 2 sources for, 0 against · Last checked

The analysis

The retrieved papers include studies specifically investigating double isotope dilution mass spectrometry (ID2MS) and double-spike isotope dilution techniques. These papers validate the high accuracy and suitability of double-spike isotopic standards for quantification tasks such as analyzing mycotoxins in food and creatinine in serum. No papers refute the claim.

Evidence for · 2
Comparison of calibration strategies for accurate quantitation by isotope dilution mass spectrometry: a case study of ochratoxin A in flour.
2024
Demonstrates that double isotope dilution mass spectrometry (ID2MS) accurately quantifies ochratoxin A in flour, falling within expected ranges for certified reference materials.
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J, B., A, B., SA, T., & JE, M. (2024). Comparison of calibration strategies for accurate quantitation by isotope dilution mass spectrometry: a case study of ochratoxin A in flour.. doi.org. https://doi.org/10.1007/s00216-023-05053-3

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More for · 1
CORRECTION OF CREATINE-CREATININE CONVERSION DURING SERUM CREATININE QUANTIFICATION BY TWO-DIMENSIONAL LIQUID CHROMATOGRAPHY AND DOUBLE-SPIKE ISOTOPE DILUTION TANDEM MASS SPECTROMETRY.
2024
Develops and validates a candidate reference method using double-spike isotope dilution tandem mass spectrometry for accurate serum creatinine quantification.
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Pineda-Cevallos, D., Menéndez, M. F., Draft, A. G. W. O., Rodríguez-González, P., & Alonso, J. I. G. (2024). CORRECTION OF CREATINE-CREATININE CONVERSION DURING SERUM CREATININE QUANTIFICATION BY TWO-DIMENSIONAL LIQUID CHROMATOGRAPHY AND DOUBLE-SPIKE ISOTOPE DILUTION TANDEM MASS SPECTROMETRY.. doi.org. https://doi.org/10.1016/j.cca.2024.117778

What does the evidence say?

The retrieved papers include studies specifically investigating double isotope dilution mass spectrometry (ID2MS) and double-spike isotope dilution techniques. These papers validate the high accuracy and suitability of double-spike isotopic standards for quantification tasks such as analyzing mycotoxins in food and creatinine in serum. No papers refute the claim.

Receipt History
first checked05 Aug 2026
judged → SUPPORTED · 6905 Aug 2026
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