While coronavirus antibodies and neutralizing titers contribute significantly to immune defense and reduce the severity of subsequent exposures, they do not provide absolute sterilizing immunity, as evidenced by documented reinfections and waning neutralization against emerging variants.
Coronavirus antibodies contribute significantly to immune defense and reduce the risk of reinfection, though they do not provide absolute immunity.
The retrieved literature shows a nuanced picture: while numerous studies (e.g., [0], [2], [3], [4], [9], [10]) confirm that coronavirus antibodies and neutralizing titers play a central role in humoral defense and correlate with protection against reinfection, other studies and clinical observations ([1], [5], [7]) demonstrate that sterilizing immunity is incomplete and breakthrough reinfections frequently occur due to waning responses or viral evolution. Therefore, the claim is contested rather than unconditionally supported.