Multiple clinical studies and systematic reviews establish that coronary artery calcium (CAC) scans are an effective, highly validated noninvasive tool for detecting early coronary artery disease and providing robust risk stratification.
The claim states that coronary artery calcium scans effectively detect early coronary artery disease. Multiple retrieved sources (papers 2, 3, 4, 5, and 9) provide strong, recent evidence supporting the diagnostic and prognostic validity of CAC scoring for identifying subclinical and early coronary artery disease. There are no refuting papers in the provided set.