Clinical anesthesia can cause physical or psychological addiction
Is it true that clinical anesthesia can cause physical or psychological addiction?
Yes. Clinical evidence indicates that certain anesthetic agents and adjuncts used in medical settings possess abuse potential and can induce psychological dependence or euphoria.
Verdict: SUPPORTED · 3 sources for, 0 against · Last checked
Several retrieved papers support the claim that clinical anesthesia agents (such as ketamine and propofol) carry risks of psychological dependence, euphoria, or abuse potential. Paper [3] notes that some anesthetics fall into controlled substance schedules associated with dependence, while papers [10] and [11] specifically document human euphoria and animal models of psychological dependence related to propofol. There are no papers refuting the claim.
Get citation
CV, P., A, K., & KC, K. (2026). Prescription of Controlled Substances: Benefits and Risks. europepmc.org. https://europepmc.org/article/MED/30726003
See more details
Get citation
L, W., Z, L., G, Q., & B, Y. (2026). Integration of epidemiological surveys, network pharmacology, and molecular docking simulation to explore the potential key targets of propofol-induced euphoria.. doi.org. https://doi.org/10.1007/s00210-025-04855-9
Get citation
L, W., T, W., Y, L., Y, S., Y, L., Z, W., Q, W., S, Z., & H, W. (2025). Unraveling the mechanisms of propofol-induced psychological dependence: a multi-omics approach linked to gut microbiota in hippocampal function.. doi.org. https://doi.org/10.3389/fmed.2025.1539467
Receipt History
Challenge the receipt
Citation formatting by citeproc-js (Frank Bennett) and the Citation Style Language project. Source and licenses.
Terms · Privacy · How verdicts work