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the claim
Certain species of jellyfish are biologically immortal.
the verdict
SUPPORTED
the evidence backs this
refutedsupported
the weight of evidence
5 sources for · 0 against

Multiple genomic and biological studies document that jellyfish species such as Turritopsis dohrnii can repeatedly undergo life cycle reversal and cellular transdifferentiation, effectively achieving biological immortality.

Evidence for · 5
Comparative genomics of mortal and immortal cnidarians unveils novel keys behind rejuvenation.
2022 · cited by 29
Turritopsis dohrnii is highlighted as a metazoan capable of repeatedly rejuvenating after reproduction, hinting at biological immortality.
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The analysis

The retrieved papers consistently support the claim that certain jellyfish species (specifically Turritopsis dohrnii and Turritopsis nutricula) exhibit life cycle reversal and rejuvenation, pointing to biological immortality. There are no papers refuting this claim.

More for · 4
Transcriptome Characterization of Reverse Development in <i>Turritopsis dohrnii</i> (Hydrozoa, Cnidaria)
2019 · cited by 27
Describes how medusae of Turritopsis dohrnii undergo reverse development and transdifferentiation in response to aging or damage.
Cellular Reprogramming and Immortality: Expression Profiling Reveals Putative Genes Involved in <i>Turritopsis dohrnii’s</i> Life Cycle Reversal
2021 · cited by 15
Examines the genetic network of cell reprogramming and reverse development in Turritopsis dohrnii as a system for researching immortality.
The conserved mitochondrial gene distribution in relatives of Turritopsis nutricula, an immortal jellyfish.
2014 · cited by 8
Identifies Turritopsis nutricula as an organism that can revert its life cycle after sexual maturity, defining itself as an immortal organism.
Nontraditional systems in aging research: an update.
2021 · cited by 7
Lists Turritopsis dohrnii alongside other organisms exhibiting longevity and immortality in aging research.
Everything we examined (12)
  1. Age reprogramming: cell rejuvenation by partial reprogramming.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  2. Back to the future: how human induced pluripotent stem cells will transform regenerative medicine.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  3. Comparative genomics of mortal and immortal cnidarians unveils novel keys behind rejuvenation.peer-reviewedsupports
  4. Transcriptome Characterization of Reverse Development in <i>Turritopsis dohrnii</i> (Hydrozoa, Cnidaria)peer-reviewedsupports
  5. Regeneration Potential of Jellyfish: Cellular Mechanisms and Molecular Insights.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  6. Cellular Reprogramming and Immortality: Expression Profiling Reveals Putative Genes Involved in <i>Turritopsis dohrnii’s</i> Life Cycle Reversalpeer-reviewedsupports
  7. Transposable elements, contributors in the evolution of organisms (from an arms race to a source of raw materials).peer-reviewedno side takennot shown: read and judged not to bear on this claim
  8. Coming of age: Annual onset of coral reproduction is determined by age rather than size.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  9. The conserved mitochondrial gene distribution in relatives of Turritopsis nutricula, an immortal jellyfish.peer-reviewedsupports
  10. Reverse development in the ctenophore &lt;i&gt;Mnemiopsis leidyi&lt;/i&gt;.peer-reviewedno side takennot shown: read and judged not to bear on this claim
  11. Nontraditional systems in aging research: an update.peer-reviewedsupports
  12. Next-generation direct reprogramming.peer-reviewedno side takennot shown: read and judged not to bear on this claim
The paper trail · every fact has a biography
first checked05 Aug 2026
judged → SUPPORTED · 8405 Aug 2026
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