Certain brain regions remain structurally unchanged over a human lifetime
the verdict
REFUTED
the evidence says no
confidence 18/100
The claim that certain brain regions remain structurally unchanged over a human lifetime is refuted by neuroimaging and developmental research showing continuous structural maturation, aging, and dynamic trajectories across all brain regions throughout life.
Evidence against · 4
Adolescence as a neurobiological critical period for the development of higher-order cognition.
2018 · cited by 612
Paper [0] discusses how brain regions undergo continuous structural maturation, stabilization, and plastic changes from adolescence into adulthood.
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More against · 3
Brain structural trajectories over the adult lifespan
2011 · cited by 213
Paper [1] demonstrates that brain structures undergo dynamic non-linear trajectories and age-related volume changes across the adult lifespan rather than remaining structurally unchanged.
The midpoint of cortical thinning between late childhood and early adulthood differs between individuals and brain regions: Evidence from longitudinal modelling in a 12-wave neuroimaging sample
2022 · cited by 2
Paper [6] quantifies the continuous structural maturation and cortical thinning processes occurring across childhood and adolescence.
Spatiotemporal dynamics of the human cortical functional hierarchy across the lifespan.
2026 · cited by 1
Paper [7] shows that the human cortical functional hierarchy and associated structural properties undergo continuous refinement and expansion across the entire lifespan.