Multiple electrophysiological studies confirm that certain populations of biological neurons, such as deep cerebellar nuclei and thalamic neurons, exhibit post-inhibitory rebound depolarization that triggers action potential firing in response to hyperpolarizing currents.
The claim states that certain biological neurons generate spikes in response to hyperpolarizing currents, which describes the well-documented physiological phenomenon of rebound bursting or post-inhibitory rebound depolarization. Multiple retrieved papers explicitly detail neurons firing spikes after hyperpolarizing current injections or inhibitory pulses (e.g., deep cerebellar nuclei neurons in [0], thalamic neurons in [1] and [2], and HVCx neurons in [11]). There are no refuting papers.